• DiscoveryProbe™ FDA-approved Drug Library

Background

DiscoveryProbe™ FDA-approved drug library includes 1971 FDA approved drugs for high throughput screening (HTS) and high content screening (HCS). It can be used to find new targets for old drugs. The bioactivity and safety of these drugs were confirmed by clinical trials. As they are all FDA-approved drugs, the drugs screened can be used for clinical testing directly.

Product Citation

Featured Products of the Library

Catalog No.Product NameSummaryTargetsCAS NumberSmiles
A3298CetirizineAntihistamineNeuroscience|Histamine Receptor83881-51-0C1CN(CCN1CCOCC(=O)O)C(C2=CC=CC=C2)C3=CC=C(C=C3)Cl
A3789Salmeterol xinafoateβ2-adrenergic receptor agonistGPCR/G protein|Adrenergic Receptor94749-08-3C1=CC=C(C=C1)CCCCOCCCCCCNCC(C2=CC(=C(C=C2)O)CO)O.C1=CC=C2C(=C1)C=CC(=C2O)C(=O)O
A4363Fluvastatin SodiumHMG-CoA reductase inhibitorMetabolism|HMG-CoA Reductase93957-55-2CC(C)N1C2=CC=CC=C2C(=C1C=CC(CC(CC(=O)[O-])O)O)C3=CC=C(C=C3)F.[Na+]
A4370Moclobemide (Ro 111163)Reversible inhibitor of MAO-AMetabolism|MAO71320-77-9C1COCCN1CCNC(=O)C2=CC=C(C=C2)Cl
A8252Nintedanib(BIBF 1120)VEGFR/PDGFR/FGFR inhibitorTyrosine Kinase/Adaptors|PDGFR928326-83-4CN1CCN(CC1)CC(=O)N(C)C2=CC=C(C=C2)NC(=C3C4=C(C=C(C=C4)C(=O)OC)NC3=O)C5=CC=CC=C5
B1792Montelukast SodiumLeukotriene receptor antagonistGPCR/G protein|CysLT1 receptor151767-02-1CC(C)(C1=CC=CC=C1CCC(C2=CC=CC(=C2)C=CC3=NC4=C(C=CC(=C4)Cl)C=C3)SCC5(CC5)CC(=O)[O-])O.[Na+]
N1674PiperineMAPK inhibitorNatural Products94-62-2C1CCN(CC1)C(=O)C=CC=CC2=CC3=C(C=C2)OCO3
N1707CoumarinPrecursor in chemical reactionNatural Products91-64-5C1=CC=C2C(=C1)C=CC(=O)O2
Download the FDA-approved-drug-library - XLSX       Download the FDA-approved-drug-library - SDF

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DiscoveryProbe™ FDA-approved Drug Library

  • Brand: ApexBio
  • Product Code: L1021
  • Availability: Pre-Order
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  • Ex Tax: $0.00

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